AB SCIEX and UOW partner to progress lipid analysis
AB SCIEX (Massachusetts, USA) and the University of Wollongong (UOW) (Wollongong, Australia) have formed a partnership to advance research in lipid analysis, as part of AB SCIEX’s academic partnership programme.
AB SCIEX (Massachusetts, USA) and the University of Wollongong (UOW) (Wollongong, Australia) have formed a partnership to advance research in lipid analysis, as part of AB SCIEX’s academic partnership programme.
The partnership agreement grants AB SCIEX with an exclusive licence to UOW’s patented lipid identification ‘ozone induced dissociation’ (OzID) technology. OzID utilises the power of mass spectrometry to separate one lipid compound from hundreds, subsequently using ozone to cut the lipid at the specific location, namely a double bond. It therefore allows the differentiation of molecules that vary only by the location of their double bonds.
The partnership research plan, funded by an Australian Research Council (ARC) Linkage Project grant, will see AB SCIEX and UOW working together to develop a standardised procedure to determine the location of double bonds within lipids. The development of a standardised procedure will enable the determination of lipid functions, such as energy storage, maintenance of cell membrane structure and roles in hormone signalling.
“Altered lipid metabolism has been linked to such global concerns as obesity, type 2 diabetes, cardiovascular disease and various cancers”, commented Dr Todd Mitchell, principal investigator from UOW’s School of Health Sciences. “Recent advances in mass spectrometry have spawned the field of lipidomics which together with proteomics, metabolomics and genomics focuses on the systemic study of complex interactions in biological systems.”
For more information, please visit:
ref=http://www.absciex.com>www.absciex.com
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.
