LCGC North America-11-01-2014

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Analysis of Complex Pharmaceuticals by Ultrahigh-Pressure Liquid Chromatography: Case Studies and Quality Control Implications

Analysis of Complex Pharmaceuticals by Ultrahigh-Pressure Liquid Chromatography: Case Studies and Quality Control Implications

Szabolcs Fekete;Nik P. Chetwyn;Davy Guillarme;Rozaliya Rangelova;Jody Richards;Dan Prudhomme;Michael W. Dong
November 1st 2014
ArticlePeer-Reviewed Articles

Experimental results and method validation data from two case studies of complex small-molecule pharmaceuticals illustrate the utility and advantages of UHPLC for quality control.

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Rapid Sample Preparation and Fast GC–MS-MS for the Analysis of Pesticides and Environmental Contaminants in Fish

Yelena Sapozhnikova
November 1st 2014
ArticlePeer-Reviewed Articles

This method allows for quick sample preparation of fish samples for the fast analysis of almost 200 targeted contaminants, including PAHs, PCBs, PBDEs, and flame retardants.

How Much Can I Inject? Part II: Injecting in Solvents Other than Mobile Phase

How Much Can I Inject? Part II: Injecting in Solvents Other than Mobile Phase

John W. Dolan
November 1st 2014
ArticleLC Troubleshooting

How large an injection can you make if the injection solvent is not matched to the mobile phase?

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Reversed-Phase HPLC Mobile-Phase Chemistry — Explained

Tony Taylor
November 1st 2014
ArticleThe Essentials

An explanation of why HPLC eluent systems are designed as they are.

Finding a Needle in a Haystack

Finding a Needle in a Haystack

John V. Hinshaw
November 1st 2014
ArticleGC Connections

Here, we examine the various way that chromatographers and chromatography data-handling systems locate and measure peaks.

Fittings and Tubing for Ultrahigh-Pressure Liquid Chromatography

Fittings and Tubing for Ultrahigh-Pressure Liquid Chromatography

Ronald E. Majors
November 1st 2014
ArticleColumn Watch

To obtain the best performance from your UHPLC system, you need the right tubing and fittings. Here is what you need to know.

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Vol 32 No 11 LCGC North America November 2014 Regular Issue PDF

November 1st 2014
ArticleIssue PDF

Click the title above to open the LCGC North America November 2014 regular issue, Vol 32 No 11, in an interactive PDF format.