Market Profile: Supercritical Fluid Chromatography (SFC)
Supercritical fluid chromatography (SFC) makes use of a supercritical fluid, typically carbon dioxide, instead of an organic or aqueous solvent, to carry the sample through the chromatography column.
The Essence of Modern HPLC: Advantages, Limitations, Fundamentals, and Opportunities
The fundamental concepts of HPLC are re-examined.
Morphological Comparison of Silica-Based Monolithic and Particulate Beds by Confocal Laser Scanning Microscopy
This analysis offers insight for optimizing the structure of monoliths.
HPLC Analysis of Very Polar Compounds in Bioanalysis
Joe Pesek answers questions about IEX, HILIC, polar-embedded, and polar-endcapped columns, and aqueous normal phase chromatography.
The Inert Flow Path Story for GC and GC–MS: Eliminating the Weakest Links
For the next improvements, we must look beyond the column.
Peaks of Interest
Fasha Mahjoor, CEO of Phenomenex (Torrance, California), has been awarded an Ellis Island Medal of Honor.
A Tribute to Ron Majors
For more than 40 years, he has been a master communicator. That's just one reason he has so many fans, and friends, around the world.
Troubleshooting GC Retention-Time, Efficiency, and Peak-Shape Problems
What problems in chromatogram may reveal, and what to do
Gradient Elution, Part IV: Dwell-Volume Problems
How can the gradient dwell volume impact results?
Hydrogen–Deuterium Exchange Mass Spectrometry: An Emerging Biophysical Tool for Probing Protein Behavior and Higher-Order Structure
HDX-MS as a means for performing routine biophysical analysis
Vol 31 No 6 LCGC North America June 2013 Regular Issue PDF
Click the title above to open the LCGC North America June 2013 regular issue, Vol 31 No 6, in an interactive PDF format.