February 2023

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What are Options to Improve My Separation? Part II: Likelihood of Separation, Adjusting Selectivity for Simple Mixtures

Dwight R. Stoll
February 2nd 2023
ArticleColumn: LC Troubleshooting

Even relatively simple mixtures are not always easy to separate. What are the options for adjusting selectivity in reversed-phase LC separations?

capillary column for gas chromatographic analysis. equipment for analytical chemistry in the laboratory.

Using Thermodynamics and Simulations to Understand Selectivity and Retention in Gas Chromatography

Nicholas H. Snow
February 1st 2023
ArticleColumn: GC Connections

By reviewing the basic thermodynamics underlying GC separations, we see how it impacts retention and method development in GC analysis.

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Analyzing Organofluorine Compounds in the Environment Using Combustion Ion Chromatography (CIC) and Other Methods

Jerome Workman Jr.
February 1st 2023
ArticleFocus On Environmental Analysis

Analysis of unidentified organofluorine compounds and known PFAS in environmental and human samples presents many challenges. Combustion ion chromatography is one technique that can help.

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How Well Do You Pipette?

Tony Taylor
February 1st 2023
ArticleColumns

You probably think you know how to pipette correctly. But do you?

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The 2023 Lifetime Achievement and Emerging Leader in Chromatography Awards

Jerome Workman Jr.
February 1st 2023
ArticleFeatured Article

Peter Schoenmakers and Emanuela Gionfriddo are the winners of the 16th annual LCGC Lifetime Achievement and Emerging Leader in Chromatography Awards, respectively.

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Analysis of siRNA with Denaturing and Non-Denaturing Ion-Pair Reversed-Phase Liquid Chromatography Methods

Pratheeba Yogendrarajah;Irene Suarez Marina;Willy Verluyten;Evelien Dejaegere;Leslie Napoletano;Jean-Paul Boon;Mario Hellings;Martin Gilar
February 1st 2023
ArticlePeer-Reviewed Article

A column with chemically modified column hardware showed improvements in analytical performance for siRNA compared to a conventional stainless-steel column.