Current Practices and Considerations for a Stability-Indicating Method in Pharmaceutical Analysis
March 1st 2014In the pharmaceutical industry, the demonstration of drug substance (DS) or drug product (DP) stability over the shelf life is an important aspect of the regulatory requirements.
The Evolution of Chiral Stationary Phases from HPLC to UHPLC
This article focuses on the progression that chiral stationary phases (CSPs), specifically developed for HPLC, are currently undergoing because of the pressing need of an easy switch to UHPLC.
Mixed-Mode HPLC Separations: What, Why, and How
March 1st 2014The mechanisms of mixed-mode chromatography are discussed with reference to the parameters that are used to optimize selectivity and retention. Illustrative examples are presented with strategies for column selection and screening to allow this technique to be quickly and effectively adopted by end users.