April 2021

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High Analytical Performance for Untargeted Aroma Profiling by Combining Dynamic Headspace Sampling, Capillary Gas Chromatography and Time‐of‐Flight Mass Spectrometry

High Analytical Performance for Untargeted Aroma Profiling by Combining Dynamic Headspace Sampling, Capillary Gas Chromatography and Time‐of‐Flight Mass Spectrometry

Tatiana Cucu;Christophe Devos;Frank David;Pat Sandra
March 31st 2021
ArticleCover Story

This article looks at the benefits of combining dynamic headspace sampling (DHS) with capillary GC–TOF-MS as a tool for untargeted analysis of aroma compounds in food and beverages. Applications for the analysis of strawberry yoghurt, chocolate, and red wine are described.

New Gas Chromatography (GC) Products for 2020–2021

New Gas Chromatography (GC) Products for 2020–2021

Nicholas H. Snow
March 31st 2021
ArticleGC Connections

“GC Connections” presents the column’s annual review of new developments in the field of gas chromatography seen at Pittcon and other venues in the past 12 months.

Hydrophobic Interaction Chromatography (HIC) for the Characterization of Therapeutic Monoclonal Antibodies and Related Products, Part 2: Practical Considerations

Hydrophobic Interaction Chromatography (HIC) for the Characterization of Therapeutic Monoclonal Antibodies and Related Products, Part 2: Practical Considerations

Szabolcs Fekete;Amarande Murisier;Liesa Verscheure;Keon Sandra;Davy Guillarme
March 31st 2021
ArticleBiopharmaceuticals Perspectives

In the second part of this review of the current state of HIC, some practical considerations are explained, including method development, selection of the phase system, combined salt systems, and possibilities to combine HIC with other chromatographic modes.

Non-targeted Analysis of Per- and Polyfluoroalkyl Substances in Surface Water using Fragment Ion Flagging

Non-targeted Analysis of Per- and Polyfluoroalkyl Substances in Surface Water using Fragment Ion Flagging

Stefan van Leeuwen;Bjorn Berendsen
March 31st 2021
ArticleFeatured Interview

LCGC Europe spoke to Stefan Van Leeuwen and Bjorn Berendsen from Wageningen Food Safety Research, The Netherlands, about a novel non-targeted approach to analyze PFASs using LC–HRMS with fragment ion flagging (FIF).