LCGC Asia Pacific-11-01-2013

Two different methods of calculating the LLOQ disagree. Which, if either, is correct?

In any field, there are "misconceptions" or "myths" that arise and are perpetuated and passed on to the next generation. These myths are often driven by a lack of understanding of the real issues by practitioners. In the first of a two-part feature from Ron Majors, the top 10 high performance liquid chromatography (HPLC) column myths are presented and attempts are made to demystify them by offering some evidence that they are untrue. This part will feature myths 10 to six.

Click the title above to open the LCGC Asia Pacific November 2013 regular issue, Vol 16, No 4, in an interactive PDF format.

Questions about how practical proposed gas chromatography (GC) method changes are often come up during optimization for speed and resolution, or while converting to a different carrier gas. Related objective measurements such as the optimum practical carrier gas velocity were defined more than 40 years ago. This instalment reviews such metrics in the light of their relevance to today's GC challenges.

A review of the latest trends in field-flow fractionation (FFF) for various types of polymer analysis.