Phenomenex, Inc.

In this technical note we show peptides and proteins identification using the bioZen nano XB-C18 column in either direct inject or trap and elute mode.

Sub-2 μm fully porous particles and core-shell particles in nano LC–MS were evaluated by separation performance and protein and peptide identifications in proteomics.

The effect of column selectivity, its importance in quality of data achieved in protein and peptide identifications in bottom-up proteomics applications, is demonstrated.

bioZen Nano 75 µm LC columns offer two advanced particle platforms, three unique column chemistries, and SecurityLINK Fitting Technology for a zero-dead volume connection.

In this application note we explore the effects of trap loadability using a bioZen 3 μm Polar C18 nano column in conjunction with the bioZen RP1 (C18) nano trap column.

In this technical note we provide a miniaturized LC–MS and SPE method for the reliable and accurate detection of viral pesticides.

Multiple selectivity options in nano LC columns allows users to tailor the chromatography for the compounds of interest to the researcher.

We demonstrate how to achieve deep proteome coverage on HeLa cell lysate using a high pH reversed-phase fractionation strategy in combination with nano flow LC–MS.

The bioZen high pH fractionation HPLC column provides superior performance using titanium hardware, minimizing nonspecific adsorption for peptide identifications.

In this technical note we explore column miniaturization effects attained by reducing column ID from 300 μm to 75 μm and its effects on sensitivity.

In this application we show reproducible results across multiple columns as well as the robust ability of the bioZen 2.6 μm XB-C18 column after 100 injections.

***Live: Wednesday, April 28, 2021 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST *** Learn to develop chiral LC and SFC methods with simple and proven strategic approach along with tips and tricks on enantiomer separations. ***On Demand until Apr. 28, 2022***

Achieving up to 70% faster GC PAH analysis. The Zebron ZB-PAH-EU and ZB-PAH-CT enable targeted selectivity for PAHs in food, the environment, electronics, and fuel.

In this application we learn how ZB-PAH-CT provides a faster Phthalates analysis comapred to other GC column

In this application we looked at the improved Dioxin analysis in Enviro matrix

In this application, we look at the improved separation and run time for PCDD and PCDF using Zebron ZB-Dioxin GC column.

This study has demonstrated that ZB-Dioxin GC columns provide improved resolution of critical pairs of dioxin in food matrix

Zebron ZB-Dioxin columns analyze dioxins and furans in food matrices. This GC innovation is a proven single GC dioxin solution that tests productivity and throughput.

Inert GC inlet liners for sample protection are easy to install. Touchless packaging allows protection from cuts, reducing contamination in the installation process.

Zebron gas management filters and Traps removes contaminants from mobile phase gases to reduce column bleed and protects sensitive GC detectors from damage.

In this application, we learn how ZB-624PLUS provides optimal separation of over 60 VOCs within 27 minutes analysis time.

***Live: Monday, March 29, 2021 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST *** In order to achieve the required sensitivity when working with small samples sizes, such as in the case of proteomic or metabolomic analysis, a low flow rate LC column is required. Micro and nano LC provides a practical solution for labs and along with the added advantage of core-shell particles, the sensitivity needs are exceeded. ***On Demand until Mar. 29, 2022***

***Live: Wednesday, March 24, 2021 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET *** Register today to expand your knowledge about new and unique GC column solutions for faster and better analysis of persistent organic pollutants like dioxins, PCBs, and PAH in food and environmental samples. Learn how these new GC column phases can greatly shorten method run time and increase sensitivity and lab productivity, making GC column selection a less painful proposition.***On Demand until Mar. 24, 2022***

***Live: Thursday, March 18, 2021 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET *** If you work with USP or European Pharmacopoeia methods (or both), then you will find this webcast to be highly informative and useful for your laboratory.***On Demand until Mar. 18, 2022***

This technical note explores a new trityl-on procedure that minimizes the risk of depurination.

Extraction of oligo therapeutics from biological samples for LC–MS bioanalysis

Using the Clarity OTX extraction protocol vendor recommendations, we have demonstrated its use to develop a method for the extraction of therapeutic oligos from plasma.

This technical note discusses 2' cleavage and RNA sample preparation prior to trityl-on Clarity QSP cartridge or high-throughput purification.

As synthetic oligonucleotide therapeutics traverse the drug-development path, there is an increasing need for TK and PK/PD studies in drug discovery and development.