Increasing Sensitivity by Scaling Down from Micro- to Nano-Flow LC

Ultrapure water from a Milli-Q® water purification system was tested for PFAS according to the draft EPA 1633 method. None of the 40 PFAS compounds tested were detected in the ultrapure water produced by a Milli-Q® IQ 7000 system fitted with a LC-Pak® polisher at the point-of-dispense, making it suitable for the most sensitive PFAS analyses by LC- MS/MS.

Ultrapure water from a Milli-Q® water purification system was tested for PFAS according to the draft EPA 1633 method. None of the 40 PFAS compounds tested were detected in the ultrapure water produced by a Milli-Q® IQ 7000 system fitted with a LC-Pak® polisher at the point-of-dispense, making it suitable for the most sensitive PFAS analyses by LC- MS/MS.

This note demonstrates efficient PFAS extraction from contaminated surface water using automated mixed-mode µSPEed® cartridges and Tecan's Resolvex® Prep.

Crucial phosphorylated compounds can be analyzed by a polymeric iHILIC-(P) Classic HILIC column and MS. The method is applicable for targeted and non-targeted metabolomics.

Learn how effective non-targeted analysis in soil samples is enabled through high resolution accurate mass in combination with intelligent data processing from Compound Discoverer.

This white paper highlights how the Thermo Scientific™ Orbitrap Exploris™ GC 240 mass spectrometer delivers unprecedented depth of analysis to gain deeper insights into every sample and advance your research.