Phenomenex, Inc.

Described in this application note are the details for an investigation of basic compound peak shape across four different alkyl C18 stationary phases that are all based upon the same core-shell HPLC/UHPLC particle morphology.

In this application, is the investigation into the relative selectivity of four different C18 stationary phases when applied to the reversed phase retention of six extremely polar artificial sweeteners.

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A straightforward separation of 10 closely related forms of vitamin E with a Kinetex 2.6 µm F5 HPLC column and under reversed-phase conditions. The 10 closely related structures were chromatographically separated by the multiple selectivity interaction mechanisms of the Kinetex F5 phase and Water/Methanol mobile phase.

This method presents the reversed-phase retention and detection of 7 polar Neonicotinoids and 4 deuterated-internal standards by LC-MS/MS and with a Kinetex 2.6 Biphenyl HPLC column. The Kinetex Biphenyl phase demonstrated significant polar compound retention and selectivity.

Described in this application note are the details for an investigation of basic compound peak shape across four different alkyl C18 stationary phases that are all based upon the same core-shell HPLC/UHPLC particle morphology.

In this application, is the investigation into the relative selectivity of four different C18 stationary phases when applied to the reversed phase retention of six extremely polar artificial sweeteners.

For this analysis, we developed a fast, robust, and efficient separation on a Kinetex 2.6µm Polar C18 phase. This is a highly robust, core-shell stationary phase capable of providing increased efficiency over fully porous products. The Kinetex Polar C18 functionality provides unique polar selectivity that was critical in effectively retaining and separating these phenolic antioxidants.

For Developed is a rapid method analyzing 16 major cannabinoids with great resolution and low backpressures.

Technote demonstrates high performance LC-MS/MS analysis of trace PFAS in water a large-volume direct injection.

Microcystins and Nodularin Analysis in Drinking Water by UHPLC-MS/MS for EPA Method 544

Utilizing the concepts of a QuEChERS extraction to prepare the broad range of Pharmaceutical and personal care products (PPCPs) from solid sediment samples for LC-MS/MS analysis

Technote demonstrates analysis of 23 PFASs in less than 5 minutes by UHPLC-MS/MS on a novel 1.6um C18 column chemistry with a positive surface charge to improve performance of the short-chained acids as well.

Sample Prep of Gen-X with WAX/GCB SPE and LC-MS/MS

Microcystins and Nodularin Analysis in Drinking Water by UHPLC-MS/MS for EPA Method 544

Utilizing the concepts of a QuEChERS extraction to prepare the broad range of Pharmaceutical and personal care products (PPCPs) from solid sediment samples for LC-MS/MS analysis

Sample Prep of Gen-X with WAX/GCB SPE and LC-MS/MS

Technote demonstrates high performance LC-MS/MS analysis of trace PFAS in water a large-volume direct injection.

Technote demonstrates analysis of 23 PFASs in less than 5 minutes by UHPLC-MS/MS on a novel 1.6um C18 column chemistry with a positive surface charge to improve performance of the short-chained acids as well.

Implementing a peptide screening SPE plate determines the appropriate choice for a wide range of chemically diverse peptides.

The optimized dual solid phase extraction (SPE) method was developed to significantly reduce the surfactant background from formulated drug products.

A HILIC solid phase extraction (SPE) and LC method that results in sensitive, effective, and a time savings for the clean-up of N-Glycans.

A fast analytical method including both sample preparation and LC–ƒMS/MS analysis of ibuprofen in human plasma.

Implementing a peptide screening SPE plate determines the appropriate choice for a wide range of chemically diverse peptides.

The optimized dual solid phase extraction (SPE) method was developed to significantly reduce the surfactant background from formulated drug products.

A HILIC solid phase extraction (SPE) and LC method that results in sensitive, effective, and a time savings for the clean-up of N-Glycans.

The development of a selective and rugged LC–MS/MS method for the quantitation of Amlodipine enantiomers in human plasma.

GenX, along with 24 other PFASs, are analyzed simultaneously to achieve sub-ppt reporting limits.

A reliable and efficient method was developed to determine the concentration sterols in olive oil by GC-FID.

The development of a selective and rugged LC–MS/MS method for the quantitation of Amlodipine enantiomers in human plasma.