Successful Analysis of Protein Biopharmaceuticals Using Ultra-Short Columns
June 20th 2023Davy Guillarme of the University of Geneva said in a talk at HPLC 2023 that short columns have shown promise, but ultrahigh-performance liquid chromatography (UHPLC) instrumentation is not yet optimized to realize their benefits.
Breakthrough MDLC–MS Method Enhances Characterization of Therapeutic Antibody Charge Variants
June 16th 2023Scientists have developed a breakthrough MDLC–MS method for in-depth characterization of charge variants in therapeutic antibodies. The innovative approach enables the detection and evaluation of rare charge variants, facilitating improved safety and efficacy in antibody development.
Unveiling Metabolite Interference for Reliable LC–MS Targeted Metabolomics Analysis
June 15th 2023New research emphasize the importance of identifying metabolite interference in LC–MS targeted metabolomics analysis to ensure accurate results. The study highlights the need for thorough investigation and resolution of metabolite interferences for reliable metabolite measurement in targeted metabolomics.