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Jinyuan Wang

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Articles

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Separation of Tryptophan Oxidized Peptides from Their Native Forms

Pranathi R. Perati;Jinyuan Wang;Valoran P. Hanko;Jeffrey S. Rohrer
October 2nd 2009

Oxidation of amino acid residues can alter a protein's biological activity, half-life and immunogenicity. Peptide maps can be used to detect oxidized peptide fragments. Peptides are commonly separated by RP-HPLC; however, hydrophobic interaction chromatography (HIC) is an alternative technique offering different selectivity.

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