Honorine Lardeux is with the School of Pharmaceutical Sciences Institute of Pharmaceutical Sciences of Western Switzerland, at the University of Geneva, in Geneva, Switzerland, and the University of Geneva, Geneva, Switzerland.
Pressure–Enhanced Liquid Chromatography as a Suitable Approach to Improve Selectivity for Large Molecule Separations
Pressure-enhanced liquid chromatography (PE-LC) offers a new approach for improving selectivity for large molecule separations. Examples shown here include short oligonucleotides in ion-pairing reversed-phase (IP-RP) liquid chromatography and larger nucleic acids in ion-exchange (IEX) chromatography.