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Dietary Supplements Analysis
Environmental Analysis
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Food and Beverage Analysis
Forensics, Narcotics
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GC–MS
Gas Chromatography (GC)
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HPLC
Ion Chromatography
LCGC Interviews
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Medical/Biological
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Process Analytical Technology (PAT)
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Sample Preparation
Size-Exclusion Chromatography (SEC)
Solid-Phase Extraction (SPE)
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Gérard Hopfgartner

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Articles

electrical lightning bolt representing an ion

The Origin and Implications of Artifact Ions in Bioanalytical LC–MS

Ron Bonner;Gérard Hopfgartner
July 1st 2022

Although well known, the extent of adduct ion formation in LC–ESI-MS/MS, and the implications for quantitative analysis and analyte characterization are not fully appreciated. We explore this problem and explain the implications for reproducibility, quantitative and qualitative analyses, and DDA and DIA.

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