Eva Pocurull

Currently, sample treatment is still the bottleneck in the development of analytical methods to analyze complex samples, especially for routine analysis where high-tech instruments are not always available. Research on the evaluation of different sample treatments is needed to achieve the sensitivity and selectivity required. This article presents a case study related to the determination of sulphonamides in liver. Different extraction strategies, including solid-liquid extraction (SLE), ultrasound-assisted extraction (UAE), and solid-phase extraction (SPE), were evaluated to produce a simple and effective extraction method.