Donald S. Risley

The authors work to develop a universal high performance liquid chromatography method that is capable of simultaneously retaining and separating both cations and anions within a single chromatographic analysis for the purpose of quantification in pharmaceutical products.

The authors discuss the advantages and disadvantages of evaporative light-scattering detection and chemiluminescent nitrogen detection for determining compounds lacking UV chromophores.

The authors descibe the use of CE with condensation nucleation light-scattering detection to analyze three pharmaceutical analytes. Because the compounds lack adequate UV chromophores, they require a more sensitive means of detection.