Carol H. Collins

This article presents an overview of high performance liquid chromatography stationary phases with enhanced stability at high pH, focusing on the methods by which they were prepared. Among the many alternatives, the authors introduce reversed phases based upon metallized silica supports that show superior performance during stability testing at high pH, when compared with conventional C18 phases based upon bare silica.

How can internal LC surfaces be made less reactive?

Stainless steel is inert – or is it?