Unravelling the Mysteries of Glycosylation
June 20th 2017A novel quantitative method combining multiple reaction monitoring (MRM) and ultrahigh‑pressure liquid chromatography coupled to mass spectrometry (UHPLC–MS) has been developed by Carlito Lebrilla and his team to study site-specific glycosylation in manufactured recombinant monoclonal antibody drugs (rmAbs). He spoke to The Column about this research.
That Old Devil Called Tasmanian
February 7th 2017A cross-disciplinary team of researchers in Tasmania from the fields of separation science, proteomics and metabolomics, immunology and zoology are on a mission to save the Tasmanian devil from extinction using metabolic fingerprinting of serum to identify biomarkers for Devil Facial Tumour Disease (DFTD). The Column spoke to Naama Karu, Rodrigo Hamede Ross, and Richard Wilson to find out more.
Identifying and Discovering Marine Lipid Biomarkers Using LOBSTAHS
October 24th 2016Discovering and identifying molecular biomarkers in large liquid chromatography–mass spectrometry (LC–MS) data sets requires automation without loss of accuracy. Benjamin Van Mooy from the Wood Hole Oceanographic Institution reveals a lipidomics strategy using LOBSTAHS to identify lipid, oxidized lipid, and oxylipin biomarkers in high mass accuracy high performance (HP) LC–MS data.
Identifying and Discovering Marine Lipid Biomarkers Using LOBSTAHS
September 22nd 2016Discovering and identifying molecular biomarkers in large LC–MS data sets requires automation without loss of accuracy. Benjamin Van Mooy from the Wood Hole Oceanographic Institution reveals a lipidomics strategy using LOBSTAHS to identify lipid, oxidized lipid, and oxylipin biomarkers in high mass accuracy HPLC– MS data.
A Collaborative Approach to Water Analysis
February 8th 2016Contaminants in surface water and drinking water supplies arising from pharmaceutical and personal care product use as well as other compound sources pose a difficult challenge for analytical chemists. Thomas Letzel from the Technical University of Munich in Germany, spoke to The Column to discuss collaborative research taking place in Europe to address contaminants of emerging concern in water analysis.
A Collaborative Approach to Water Analysis
December 10th 2015Contaminants in surface water and drinking water supplies arising from pharmaceutical and personal care product use as well as other compound sources pose a difficult challenge for analytical chemists. Thomas Letzel from the Technical University of Munich in Germany spoke to LCGC to discuss collaborative research taking place in Europe to address contaminants of emerging concern in water analysis.
Environmental Forensics in the Workplace
November 5th 2015Populations worldwide are exposed to polychlorinated biphenyls (PCBs) that can be harmful to human health. The Column spoke to David Megson from Ryerson University in Toronto, Canada, about recent developments in assessing human exposure to PCBs and chiral enantiomer fractions (EFs) in the workplace.
Reproducible HILIC Method for Paralytic Shellfish Toxins
October 26th 2015A new chromatographic method to detect paralytic shellfish toxins (PSTs) in food has been developed by a team of scientists from the Swedish Research Agency.PSTs pose a threat to seafood and drinking water from natural contamination, but could also be used to deliberately contaminate food, according to the authors.
Untargeted Metabolomics for Marine Pollution Analysis Using GC–MS
September 8th 2015Marine polychaetes are a common type of annelid worm widely spread in marine environments. Raquel Fernandez from the University of Copenhagen, Denmark, spoke to Aladair Matheson of The Column about her innovative approach to developing an untargeted method to monitor polychaetes and assess their potential use in environmental monitoring of oil spills.
Improving Hydraulic Fracturing Fluid Analysis Using the Kendrick Mass Defect
August 21st 2015The Kendrick mass defect combined with liquid chromatography quadrupole time-of-flight mass spectrometry (LC–QTOF-MS) can offer a variety of benefits to analysts investigating groundwater contamination. The Column spoke to Thomas Borch from Colorado State University in Colorado, USA, about his work in this area to find out more.
Analysis of Wastewater in New York State Indicates Illicit Drug Consumption
July 7th 2014The study of sewage using chromatographic techniques is a rapidly expanding area that can provide insights into the consumption of illicit drugs. Measuring illicit drug concentrations can provide authorities with a close to real time identification of consumption trends and rates in specific geographical areas.
Marine Pollution Analysis: The Deepwater Horizon Oil Spill
February 20th 2014Chris Reddy from the Woods Hole Oceanographic Institution (WHOI) spoke to Alasdair Matheson of The Column about the role of chromatography in the ongoing environmental analysis of the Deepwater Horizon oil spill, how GC×GC works in practice, and why this oil spill led to the return of thin layer chromatography (TLC) to his laboratory.
Day 3 of the Pittcon Audio & Video Theater
March 2nd 2010Wednesday?s Pittcon Audio & Video Theater will be dedicated to CHROMacademy. CHROMacademy is a cutting-edge e-learning programme that LCGC is launching in collaboration with Crawford Scientific. The site will provide continual professional development for chromatographers to make them more effective in the workplace.
Day 1 of the Pittcon Audio & Video Theater
February 25th 2010Monday morning LCGC North America and LCGC Europe will launch the first Pittcon Theater sessions. This cutting-edge multimedia project will include live interviews with leading experts from the world of analytical chemistry and will cover the latest developments, applications and trends in the fields of chromatography and spectroscopy. Editor-in-chief of LCGC North America, Dave Walsh and Editorial Director of LCGC Europe, Peter Houston, will host these illuminating sessions.