Application Notes: General

This application note shows that a single column to be used for the analysis of a wide range of molecular sizes, from intact proteins and monoclonal antibodies to digested peptides.

This application note describes the benefits of automated gravimetric liquid dispensing compared to traditional manual stock solution preparation in a volumetric flask.

This application note examines a group of UHPLC columns and their analytical conditions using synthesized miRNA samples.

Here, we introduce HPLC columns with wider pores designed to analyze the characterization of the first-dimensional structure of peptides in reverse phase condition.

This application note introduces the usefulness of wide pore columns, targeting large macromolecules.

This guide describes how you can improve the efficiency of your chromatographic workflow with our manual, automated, and robotic solutions

Application of C18, 1.6 µm UHPLC columns in the analysis of insulin with strong and weak ion pairing agents to see how they increase the height of the insulin peak.

This application note covers high-resolution oligonucleotide analysis using a wide pore (WP) C18 1.6 µm UHPLC column.

This application note explains an integrated workflow with automatic flow of weighing data from sample and standard preparation to chromatographic analysis in the HPLC.

Read our application note to find out how gravimetric solution preparation can significantly reduce the cost of your trace metal analyses.

This application note describes the benefits of using a fully automated robotic solution for preparing samples and standards for chromatographic analyses.

This application note presents a quick and easy way to prepare accurate reference standards for HPLC and other chromatographic (analytical) methods.

This application note introduces application data obtained by using FlexFire SEC Columns that have adopted newly developed superior silica.

Time to results can be significantly reduced with the use of RapidFire high-throughput mass spectrometry (MS). With this technique, a lab’s next great innovation can be brought from conception to reality in a timely and efficient manner.

This brief communication highlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.

Analysis of volatile organics in soils using the CDS 8500 Automated Purge and Trap System.

This application note demonstrates the performance of multi-detector asymmetrical flow field-flow fractionation for the characterization of macromolecules in beer.

Lipid nanoparticles (LNPs) are effective non-viral carriers, which are widely used as delivery vehicles for gene-based drugs such as messenger RNA (mRNA). To mitigate safety risks and ensure product efficacy, it is important to comprehensively characterize the lipids used for LNPs and their related impurities, as well as the mRNA integrity, purity and its critical quality attributes (CQAs).

Helium supply is unreliable. Prices are increasing, supply is decreasing, and the need for an alternative carrier gas is growing. So does your lab reduce its helium consumption or switch to an alternative carrier gas?

An introduction to microchamber sampling for the rapid screening of chemical emissions from construction materials and consumer products

This application note shows the robust, reproducible analysis of trace VOCs in hydrogen fuel by TD–GC–MS/SCD.

Theory and practice of using axial and radial samplers for passive (diffusive) monitoring of VOCs in air

It is essential to understand the pharmacokinetic profiles and toxicological concerns associated with substances/compounds produced into reference standards trusted for analytical testing and development of high quality pharmaceutical therapies.

Personal exposure testing of nitrous oxide can be done via passive and breath sampling using Markes’ Bio-VOC and TD–GC.

Advice on which sorbent to use for pumped (diffusive) tube monitoring of various vapour-phase organics; suggests parameters for conditioning and storing packed tubes.

How TD benefits a wide range of industrial emissions testing applications, offering compatibility with both whole-air/gas containers and sorbent tubes

Demonstrating the efficient use of online and off-line trace-level analysis of thermally labile sulfur compounds by TD–GC; used in air monitoring and industry.