HPLC 2011: Day 1
20 June — Budapest, Hungary: Welcome to the first day of coverage of HPLC 2011, which is being held at the Budapest Congress and World Trade Center in Hungary.
HPLC 2011 is a major highlight in the chromatography calendar and this year’s chairman Attila Felinger, from the Department of Analytical and Environmental Chemistry at the University of Pecs in Hungary, has gathered a stellar cast of separation scientists from industry and academia to reveal the latest developments in their fields.
The scientific programme will focus on innovative methods and technology in chromatography and includes eight plenary lectures, thirty keynote lectures and eighty-seven lectures, as well as tutorials, short courses, poster sessions and an exhibition from leading vendors in the chromatography sector.
These daily show guides from LCGC Europe and LCGC North America will keep you abreast of what is happening at HPLC 2011.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.