Using SRM and H-SRM on an Integrated UHPLC-MS Platform for Sensitive, Accurate and Reproducible Quantification of Perfluorinated Compounds in Human Breast Milk
Using SRM and H-SRM on an Integrated UHPLC-MS Platform for Sensitive, Accurate and Reproducible Quantification of Perfluorinated Compounds in Human Breast Milk.
Perfluorinated compounds (PFCs) are pollutants that bioaccumulate in animals and humans and have been linked to developmental, reproductive and systemic toxicity. PFCs are detectable in human serum and breast milk and have even been found in the blood of newborns, through lactational transfer from mothers. The potential toxicity and bioaccumulation of these chemicals has led to an increase in the need to monitor PFCs and assess their risk to humans. This article discusses how PFCs can be accurately and reproducibly detected at ppt concentrations in neat solution and human breast milk using selected reaction monitoring (SRM) and highly selective reaction monitoring (H-SRM) on an integrated ultra high performance liquid chromatography mass spectrometry (UHPLC–MS) platform.
Silvia Radenkovic on Her Research and Passion for Scientific Collaboration
April 3rd 2025Radenkovic is a PhD candidate at KU Leuven and a member of FeMS. Her research focuses on inborn metabolic disorders (IMD), like congenital disorders of glycosylation (CDG), omics techniques such as tracer metabolomics, and different disease models.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Quantifying Microplastics in Meconium Samples Using Pyrolysis–GC-MS
March 26th 2025Using pyrolysis-gas chromatography and mass spectrometry, scientists from Fudan University and the Putuo District Center for Disease Control and Prevention detected and quantified microplastics in newborn stool samples.
