This Application Note shows the transfer of a standard HPLC method to a UHPLC method for the analysis of 13 DNPH-derivatized aldehydes and ketones. By transferring the method from HPLC to UHPLC, the analysis time and solvent consumption was reduced by approximately 90 %.
Pick Your Poison. Isolation of Paclitaxel (Mar 2025)
March 7th 2025The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. The isolation of paclitaxel from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.