Spark Holland B.V. in Partnership with Axel Semrau GmbH & Co. KG
Spark Holland B.V. (Emmen, The Netherlands), a supplier of analytical instrumentation transferred its direct sales and service activities for its online solid phase extraction (SPE) products and services in Germany to Axel Semrau GmbH & Co. KG (Sprockhövel, Germany).
Spark Holland B.V. (Emmen, The Netherlands), a supplier of analytical instrumentation transferred its direct sales and service activities for its online solid phase extraction (SPE) products and services in Germany to Axel Semrau GmbH & Co. KG (Sprockhövel, Germany). The transaction allows Axel Semrau to provide online SPE solutions to customers and markets in Germany.
Axel Semrau will become a “Value Added Partner” of Spark Holland, and as such, it will provide more value to the product offering along with a higher level of technical and customer support. The products supported are the online SPE systems, which include Spark’s brand names Symbiosis Pico and Symbiosis Pharma. Product offerings also include consumables, such as SPE cartridges.
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.
