Advice on which sorbent to use for pumped (diffusive) tube monitoring of various vapour-phase organics; suggests parameters for conditioning and storing packed tubes.
Progress with Alternative Solvents for SIFT-MS: 2024 Update
January 30th 2025Explore advancements in utilizing alternative solvents for SIFT-MS. This tech note introduces three new solvents—acetonitrile, N,N'-dimethylpropyleneurea (DMPU), and propylene glycol (PG)—and highlights the enhanced sensitivity and applications of existing solvents like triacetin. The findings demonstrate significant benefits in analyzing diverse VOCs while addressing challenges in method development.
SIFT-MS: A Highly Reproducible Real-Time Trace Gas Analysis Technology
January 30th 2025SIFT-MS instruments show exceptional reproducibility. By comparing standardized analytical methods on multiple instruments, it demonstrates high consistency in trace gas quantitation with 95% confidence intervals below 21% for the Syft Tracer and 38% for legacy devices. The findings emphasize Syft's commitment to advancing reliable, real-time analysis solutions for diverse applications.
Rapid and Quantitative Screening of Nitrosamines in Drug Products Using Headspace-SIFT-MS
January 30th 2025This study demonstrates that headspace-SIFT-MS meets United States Pharmacopeia (USP) criteria for six nitrosamines, achieving low limits of quantitation (0.06 ppm for NDMA and 0.03 ppm for NDEA) even in complex drug matrices. With high recovery rates and significant reductions in solvent usage, consumables, and operational complexity compared to traditional chromatographic methods, the Syft Tracer Pharm11 solution is an efficient screening tool for nitrosamines and volatile impurities.