Pacesetter – The new GCMS-QP2010 Ultra with ChromSquare Software
Shimadzu?s brand-new GCMS-QP2010 Ultra delivers unsurpassed scan speeds.
Shimadzu’s brand-new GCMS-QP2010 Ultra delivers unsurpassed scan speeds. With a maximum of 20,000 amu/s the speed has been doubled compared to the previous generation GCMS. This extraordinary performance is achieved by the patented Advanced Scanning Speed Protocol (ASSP) increasing the sensitivity for compounds with high molecular masses by a factor of 5.
High Speed data acquisition for Comprehensive GC with quadrupole MS detection
The high speed data acquisition of the Ultra leads to higher resolution of peaks and better identification power for data from Comprehensive GCMS analysis. The new software for analysis of Comprehensive Chromatography, ChromSquare software provides all means for quantitative and qualitative analysis. It provides in-depth insights at any point in the process and uses up to five libraries at the same time. Simultaneous display of raw data chromatogram and contour plot in one window gives users an overview of their data at any time.
For further details please visit www.shimadzu.eu
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
LC/MS Based Characterization Workflow of GLP-1 Therapeutic Peptide Liraglutide and Its Impurities
January 14th 2025This application note demonstrates a liquid chromatography/quadrupole time-of-flight mass spectrometer (LC/Q-TOF MS) workflow for the identification and characterization of therapeutic peptides.
