Oligonucleotide Analysis by Ion-Pair Chromatography

Per- and polyfluoroalkyl substances demand precise detection. YMC-Triart C18 columns ensure superior separation and accurate quantification, even in complex matrices.

This application demonstrates the LC-MS/MS analysis of 46 PFAS and 25 surrogate compounds in solid matrices using a newly developed, cost-effective workflow.

A comparison made between a stainless steel hardware column and an INERT column using the same lot of HALO 90 Å C18, 2.7µm results in tailing factor and area improvement using the HALO®INERT column.

Using HALO®Elevate C18 and a high pH mobile phase obtains a great separation of drugs of abuse and metabolites without the use of a specialized stationary phase.

The positively charged surface chemistry of HALO® PCS Peptide delivers narrower peak width, higher signal response and double the peak capacities compared to standard uncharged peptide materials

Over the course of 5000 injections, the HALO®Elevate C18 1.5 mm ID column demonstrates stability and robustness in the stationary phase and the column hardware, with no significant changes to the retention time, peak shape, and back pressure.