Nitrosamines, Meeting Regulatory Requirements

Abacavir and Lamivudine in combination are used with other medications to treat Human Immunodeficiency Virus (HIV) infection. In this technical note, we report the separation of Lamivudine from its related chiral and diastereomeric impurities in Abacavir and Lamivudine tablets per the USP monograph. The allowable adjustments pertaining to gradient separations are highlighted together with the necessary calculations that are required for the adjusted method conditions to remain compliant with the original monograph.

This applications notebook provides background information on GLP-1 analogues, together with information on the columns suitable for their purification and analysis. Finally it provides a range of reversed phase, size exclusion and preparative applications for a number of GLP-1 analogues.

This white paper explores L/dp ratio for pharmacopeia allowable adjustments. It considers efficiency, explaining why L/dp ratio can be used as a proxy for efficiency, and illustrates the allowable adjustments through reviewing at a selection of different monographs.

This white paper provides an in depth consideration of the new European Pharmacopeia monograph for the analysis of chlorhexidine and it’s related impurities. The white paper considers both column batch variation and system dwell volume.

A simplified SPE procedure using UCT’s HL DVB polymeric sorbent for the analysis of 64 Pharmaceuticals and Personal Care Products (PPCPs) in water according to EPA Method 16

Tire wear particles left on roads can cause marine and air pollution. Py-GC-MS identifies and quantifies microplastics present in air, sand, soil, and other materials.