Due to the highly polar nature of saccharides, the analysis of sugars is typically achieved using Hydrophilic Interaction Chromatography (HILIC). Using a high polarity packing material, separation is based on the hydrophilic interactions of the sugars on the stationary phase surface typically using an eluent with a majority of polar organic solvent.
Green Chemistry: What is it (and What Is It Not)? And How Does It Apply to Gas Chromatography?
October 31st 2024Everyone is talking about sustainability, and organizations are creating sustainability programs. But what does green chemistry really mean, and how does it apply to gas chromatography?
HILIC Peptide Retention Times Predicted Using New Approach
October 29th 2024Manitoba Centre for Proteomics and Systems Biology scientists produced a new means of predicting peptide retention times for hydrophilic interaction liquid chromatography (HILIC) at acidic pH in formic-acid based eluents.