This month's column begins our annual roundup of new column technologies shown at the Pittsburgh Conference. In part I, we'll look at HPLC columns and packings for reversed-, normal-, and bonded-phase; ion-exchange; ion; size-exclusion; and large- and preparative-scale chromatography as well as specialty columns.
LCGC 18(3), 262–285 (2000).A Novel Two-Step Workflow for Extracting Clean Mass Spectra in LC×LC–HRMS Data
March 3rd 2025LCGC International spoke to Paul-Albert Schneide and Oskar Munk Kronik about the development and application of a novel two-step workflow—mass filtering (MF) combined with multivariate curve resolution (MCR)—for extracting clean mass spectra from trace-level compounds in LC×LC–HRMS data.