Native online SCX-MS of monoclonal antibodies

A comparison made between a stainless steel hardware column and an INERT column using the same lot of HALO 90 Å C18, 2.7µm results in tailing factor and area improvement using the HALO®INERT column.

The positively charged surface chemistry of HALO® PCS Peptide delivers narrower peak width, higher signal response and double the peak capacities compared to standard uncharged peptide materials

A mix of four antidepressants is separated using the HALO®PCS (positive charged surface) C18 column demonstating the improved tailing factor and efficiency when compared to a traditional (uncharged) C18 stationary phase.

The HALO® OLIGO C18 2.7 µm column outperformed an FPP Oligo C18 column in oligonucleotide separations, achieving faster separations while maintaining efficiencies comparable to a 1.9 µm FPP with more than half the backpressure.