Multi-Dimensional Chromatography
The Wednesday afternoon session on multi-dimensional chromatography includes two talks from instrument vendors.
The Wednesday afternoon session on multi-dimensional chromatography includes two talks from instrument vendors.
The first presentation, “The Analysis of Petrochemical Samples by 2D-GC Combined with High-Resolution Mass Spectrometry” by A. John Dane, Koji Okuda, and Robert B. Cody of JEOL USA, Inc., discusses comprehensive two-dimensional gas chromatography (GCxGC) used in combination with high-resolution mass spectrometry (HRMS) for the analysis of complex mixtures. The talk will report on details of the analysis of several petrochemical samples using GCxGC in combination with a new high-resolution time-of-flight (TOF) mass spectrometer.
The next talk, “GC×GC with Simultaneous Mass Spectrometry/Flame ionization Detection for Complete Petrochemical Analysis,” presents the work of Pete Grosshan, Matthew Edwards, Dave Wevill, Chris Hall, and Nick Bukowski of Markes International. The talk will discuss the use of parallel detection GC×GC to enable both targeted and nontargeted approaches to be performed simultaneously-with TOF-mass spectrometry (MS) for confident identification and a flame ionization detector (FID) for robust quantitation. The speakers also plan to demonstrate tandem ionization for simultaneous acquisition of both hard and soft EI spectra-thus, unlocking the fine detail of the sample composition.
This session will be held from 2:30 to 3:20 pm in room 370 E.
Best of the Week: Food Analysis, Chemical Migration in Plastic Bottles, STEM Researcher of the Year
December 20th 2024Top articles published this week include the launch of our “From Lab to Table” content series, a Q&A interview about using liquid chromatography–high-resolution mass spectrometry (LC–HRMS) to assess chemical hazards in plastic bottles, and a piece recognizing Brett Paull for being named Tasmanian STEM Researcher of the Year.
Using LC-MS/MS to Measure Testosterone in Dried Blood Spots
December 19th 2024Testosterone measurements are typically performed using serum or plasma, but this presents several logistical challenges, especially for sample collection, storage, and transport. In a recently published article, Yehudah Gruenstein of the University of Miami explored key insights gained from dried blood spot assay validation for testosterone measurement.
Determination of Pharmaceuticals by Capillary HPLC-MS/MS (Dec 2024)
December 19th 2024This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis of pharmaceutical drugs in model aqueous samples.
