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A Novel Two-Step Workflow for Extracting Clean Mass Spectra in LC×LC–HRMS Data
March 3rd 2025LCGC International spoke to Paul-Albert Schneide and Oskar Munk Kronik about the development and application of a novel two-step workflow—mass filtering (MF) combined with multivariate curve resolution (MCR)—for extracting clean mass spectra from trace-level compounds in LC×LC–HRMS data.