Malvern Instruments (Malvern, UK) has opened a new applications laboratory in Sao Paulo, Brazil.
Malvern Instruments (Malvern, UK) has opened a new applications laboratory in Sao Paulo, Brazil. Located at the existing facility of Malvern’s parent company, Spectris, the laboratory will provide assistance to customers and will be equipped with support for particle characterization, protein measurement and rheology systems.
Edna Alvarez, Latin America Sales Manager for Malvern, said: “I am delighted that Malvern has been able to set up such an excellent laboratory facility and very much look forward to welcoming customers from Brazil and elsewhere in South America. We have long enjoyed a very successful relationship with Altmann SA, our dealer in Brazil, and I am especially pleased to be providing them with access to further local demonstration, technical and applications support.”
This follows the opening in March 2012 of a facility in Houston, Texas, USA.
For more information please visit www.malvern.com
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.