J.T.Baker® Brand High Purity Solvents and Reagents — ULTRA LC/MS, LC/MS and HPLC Solvents
The Avantor? J.T.Baker® high purity solvents and reagents will give you the performance you need with minimal risk of contaminants that can limit accuracy and productivity and maximize the sensitivity and detecting power of your instrumentation.
The Avantor™ J.T.Baker® brand high purity solvents and reagents will give you the performance you need with minimal risk of contaminants that can limit accuracy and productivity and maximize the sensitivity and detecting power of your instrumentation.
Our ULTRA LC/MS grade is ideal for cutting-edge applications such as proteomics, pharmacokinetics, clinical research and drug discovery. Designed to meet the needs of the world’s most demanding UHPLC and LC/MS research and analytical testing applications. ULTRA LC/MS solvents are suitability tested for function-applicable mass spectrometry with both electrospray positive and negative modes.
For more routine applications, our LC/MS solvents and blends are function-tested and optimized for minimal impurities and interference-free baselines, giving you performance you can trust in the mobile phase - every time.
Our HPLC solvents maximize throughput and ease-of-use without sacrificing efficiency or reproducibility. Our solvents and modifiers also help you get optimum performance from sensitive instrumentation.
Visit: www.avantormaterials.com for more information or send us an email: avantor.emea@avantormaterials.com
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.
