Innovative cryogen-free ambient air monitoring of trace-level air toxics at high humidity

This application note explores an efficient, helium-free method for continuous monitoring of ozone precursors in ambient air, aligned with EPA PAMS requirements. By using hydrogen as the carrier gas, this approach achieves faster run times, stable retention times, and effective separation of volatile organic compounds. A case study from New York City highlights the system's performance in urban air quality monitoring, capturing shifts in pollutant levels during periods of reduced traffic. With remote operability and cryogen-free functionality, this method offers a reliable and sustainable solution for real-time air quality analysis in both urban and remote environments.

This application note outlines an analytical approach that meets the stringent requirements of EPA Method 327 for monitoring ethylene oxide and other hazardous air pollutants. The key innovation is the ability to achieve the required sensitivity without the need for liquid cryogen cooling, enabling more cost-effective and productive monitoring. Highlights include a 10 ppt method detection limit for ethylene oxide, effective management of sampling bias and chromatographic interferences, and straightforward method transfer between laboratories. The flexible, cryogen-free preconcentration system enables large-volume sampling to boost sensitivity while simplifying operation, making it an attractive solution for implementing the new EPA method.

Ultrapure water from a Milli-Q® water purification system was tested for PFAS according to the draft EPA 1633 method. None of the 40 PFAS compounds tested were detected in the ultrapure water produced by a Milli-Q® IQ 7000 system fitted with a LC-Pak® polisher at the point-of-dispense, making it suitable for the most sensitive PFAS analyses by LC- MS/MS.

Ultrapure water from a Milli-Q® water purification system was tested for PFAS according to the draft EPA 1633 method. None of the 40 PFAS compounds tested were detected in the ultrapure water produced by a Milli-Q® IQ 7000 system fitted with a LC-Pak® polisher at the point-of-dispense, making it suitable for the most sensitive PFAS analyses by LC- MS/MS.

This note demonstrates efficient PFAS extraction from contaminated surface water using automated mixed-mode µSPEed® cartridges and Tecan's Resolvex® Prep.

Crucial phosphorylated compounds can be analyzed by a polymeric iHILIC-(P) Classic HILIC column and MS. The method is applicable for targeted and non-targeted metabolomics.