The high-performance liquid chromatography (HPLC) market is estimated to grow to $8.22 billion by 2033, according to a report published by Research and Markets, a Dublin, Ireland-based market research firm. This is an increase from 2023, when the HPLC market was estimated to be at $5.23 billion.
Per the firm’s website (1), the report estimates the market is growing at a compound annual growth rate (CAGR) of 4.61% during the period forecasted. The trajectory of this market has been stimulated by technological advancements in the global high-performance liquid chromatography ecosystem that show great potential, with many key players in the market including Thermo Fisher Scientific, Shimadzu Corporation, and Agilent Technologies actively engaged in the development and integration of artificial intelligence (AI) with high-performance liquid chromatography (HPLC) systems.
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While the global HPLC market is exhibiting indications of decelerated growth, heightened competition, and saturation in key applications, signaling a shift toward maturity, the report’s findings indicate that the market has yet to reach that stage. Factors such as continued technological innovations and market expansion in emerging regions continue to drive growth, placing it within the late maturity phase. While the report acknowledges that mature traits are apparent, it is the opinion of the publishers that complete maturity has currently not been realized.
The report further recognizes that the global market for HPLC demonstrates diverse regional impacts which are influenced by numerous factors, such as healthcare infrastructure, regulatory frameworks, and cultural attitudes toward analytical techniques. In regions such as North America and Europe, where the market for such devices is well-established, there is a notable emphasis on advanced analytical methods, including HPLC and ultra high-performance liquid chromatography (UHPLC), resulting in the adoption of HPLC systems across various sectors, including clinical research and forensics. Furthermore, the presence of robust healthcare systems and substantial investment in research and development in these regions further bolsters innovation in the field. Similarly, the Asia-Pacific region has also been participating in rapid market growth driven by the increasing awareness of technological advancements, expansion of healthcare facilities, and rising disposable incomes among consumers.
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The HPLC market has seen an influx of new products, as indicated in LCGC International’s recent article on the subject (2). For example, in the past year, Knauer introduced a new Azura UHPLC 1240 bar system, that targets high-throughput UHPLC and MS/MS applications. Agilent released the new 1290 Infinity II Bio Online LC system that blends high performance and biocompatible features for the analysis and real-time monitoring in pharmaceutical processing. Waters also released the Alliance iS HPLC system, which includes a quaternary pump and UV absorbance detector that is meant to reduce common laboratory errors, operator training requirements, and method transfer time.
It is this influx of ongoing innovation in HPLC technology, combined with increased investment in research and development initiatives, that reinforces the technique, as well as the equipment to successfully perform it, as necessary assets in both industrial and academic investigation. The report anticipates that this rising need from the biotechnological and pharmaceutical sectors will result in manufacturers catering to the dynamic demands and standards prevalent within these flourishing industries.
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