HILIC: A Powerful Separation Mode for a Broad Range of Applications
The rising interest in HILIC can be demonstrated by the growing number of publications and applications over the last 10 years. Applications range from food and nutrition, to cosmetics, pharmaceuticals, and bioanalysis.
The rising interest in HILIC can be demonstrated by the growing number of publications and applications over the last 10 years. Applications range from food and nutrition, to cosmetics, pharmaceuticals, and bioanalysis.
HILIC Peptide Retention Times Predicted Using New Approach
October 29th 2024Manitoba Centre for Proteomics and Systems Biology scientists produced a new means of predicting peptide retention times for hydrophilic interaction liquid chromatography (HILIC) at acidic pH in formic-acid based eluents.
Systematic Evaluation of HILIC Stationary Phases for MS Characterization of Oligonucleotides
Hydrophilic interaction chromatography–mass spectrometry (HILIC-MS) offers a flexible and efficient alternative to ion-pairing reversed-phase liquid chromatography (IP-RPLC) for oligonucleotide analysis, with column selectivity and mobile phase pH being key factors in optimizing retention and detection.
