From Screening to Confirmation: A Comprehensive Food Safety Analysis from Initial DIA Screening to Automatic Reinjection for Suspect Confirmation
Webinar Date/Time: Wed, Jun 28, 2023 1:00 PM EDT
Reducing the amount of time from screening to confirmation. A workflow solution for the analysis of pesticides in complex food matrix with data independent acquisition and automatic targeted reinjection on a new LC/Q-TOF.
Register Free: https://www.chromatographyonline.com/lcgc_w/suspect-confirmation
Event Overview:
A new novel prototype LC/Q-TOF system is leveraged for the screening of pesticides in complex matrix utilizing data independent acquisition (DIA). DIA allows for retroactive analysis of an ever-growing list of emerging contaminants. Confident identification is made through a combination of high-resolution, extended dynamic range, stable accurate mass, and isotopic fidelity which can be quickly and easily analyzed via the customizable LC Screener Tool, simplifying the processing of complex screening data. Along with this screening capability, new automated software, Intelligent Reflex, uses the results and allows for the reinjection and targeted confirmation of questionable and/or identified residues. The combination of screening and automated targeted reinjection reduces the amount of time from sample introduction to confident characterization.
Key Learning Objectives:
- Introduction to the new LC/Q-TOF
- Learn how data independent acquisition (DIA) and the LC Screener Tool allow for easy and simple screening of pesticides in complex matrix with confidence.
- Understand how the ability to confirm identified and tentatively identified compounds through automatic reinjection reduce complete analysis time and manual reinjection decisions.
Who Should Attend:
- Lab manager in Food safety and environmental labs
- Principle Investigators in Food safety and environmental research
Speakers:
Cate Simmermaker
LC/MS Applications Engineer
Agilent Technologies
Cate Simmermaker is an LC/MS Applications Engineer with Agilent Technologies working primarily with high-resolution mass spectrometry in small molecule analysis. Cate has worked in applications including metabolomics, food safety, and forensics on Q-TOF and QQQ platforms. She is currently working to complete her Ph.D. in Chemistry from the University of the Pacific and received a Master’s in Biochemistry from San Francisco State University.
Christian Klein
LC/Q-TOF Marketing Product Manager
Agilent Technologies
After finishing his MSc in Chemistry at Wuerzburg, Germany, Christain Klein moved to the Max-Planck-Institute for Biochemistry in Martinsried, Germany. The title of his Ph.D. thesis (2005), conducted in the Oesterhelt group, was “Proteome analyses of Halobacterium salinarum” and included MALDI and ESI mass spectrometry, as well as 2-dimensional gel-electrophoresis, with a general focus on membrane proteins. In 2006, he went as a PostDoc to Ghent, Belgium to study the separation of membrane proteins via diagonal chromatography with Joel Vandekerckhove. He then returned to the Max-Planck-Institute, working on separation and identification methods for small proteins, before joining the corporate environment in 2007 as a demo chemist with a focus on proteomics applications. In 2010, he joined the R&D team with Agilent, working on LC/MS Q-TOF systems including ion mobility. Since 2018, he is the LC/Q-TOF and IM-QTOF Product Manager.
Register Free: https://www.chromatographyonline.com/lcgc_w/suspect-confirmation
Inside the Laboratory: The Richardson Group at the University of South Carolina
November 20th 2024In this edition of “Inside the Laboratory,” Susan Richardson of the University of South Carolina discusses her laboratory’s work with using electron ionization and chemical ionization with gas chromatography–mass spectrometry (GC–MS) to detect DBPs in complex environmental matrices, and how her work advances environmental analysis.
Analytical Challenges in Measuring Migration from Food Contact Materials
November 2nd 2015Food contact materials contain low molecular weight additives and processing aids which can migrate into foods leading to trace levels of contamination. Food safety is ensured through regulations, comprising compositional controls and migration limits, which present a significant analytical challenge to the food industry to ensure compliance and demonstrate due diligence. Of the various analytical approaches, LC-MS/MS has proved to be an essential tool in monitoring migration of target compounds into foods, and more sophisticated approaches such as LC-high resolution MS (Orbitrap) are being increasingly used for untargeted analysis to monitor non-intentionally added substances. This podcast will provide an overview to this area, illustrated with various applications showing current approaches being employed.
RAFA 2024 Highlights: Contemporary Food Contamination Analysis Using Chromatography
November 18th 2024A series of lectures focusing on emerging analytical techniques used to analyse food contamination took place on Wednesday 6 November 2024 at RAFA 2024 in Prague, Czech Republic. The session included new approaches for analysing per- and polyfluoroalkyl substances (PFAS), polychlorinated alkanes (PCAS), Mineral Oil Hydrocarbons (MOH), and short- and medium-chain chlorinated paraffins (SCCPs and MCCPs).
