Digital Update
CHROMacademy is a chromatography e-learning programme that provides continuing profesional development for chromatographers to make them more effective in the work place. There are over 3000 pages of e-learning on HPLC, GC, MS and Sample Preperation techniques to improve practical knowledge for the absolute novice (What is Chromatography?) to the expert who needs a refresher in a particular topic (Advanced Topics in LC–MS Spectral Interpretation, for example).
CHROMacademy webinars
CHROMacademy is a chromatography e-learning programme that provides continuing profesional development for chromatographers to make them more effective in the work place. There are over 3000 pages of e-learning on HPLC, GC, MS and Sample Preperation techniques to improve practical knowledge for the absolute novice (What is Chromatography?) to the expert who needs a refresher in a particular topic (Advanced Topics in LC–MS Spectral Interpretation, for example). The site can be also used for induction training or programmed learning activites and there are tutorials and assessments built into all learning modules to check progress. The first official webinar: Essential Guide 1: Split /Splitless Injection for Capillary GC attracted 568 visitors. The recorded session is available via the CHROMmunity at http://chrommunity.chromacademy.com (under the WEBCASTS Tab). The next Webcast is: Essential Guide 2: Mobile Phase Optimization Strategies for Reversed Phase HPLC.
Radiochromatography software
Lablogic Systems has released Version 4.0.5 of its Laura radiochromatography software, which the company claims brings together more than 150 improvements and innovations from the last twelve months. These changes include the optimization of the Active Counting Mode facility, which is reported to make it more reproducible with better resolution, sensitivity and control. Also included are interfaces for the iScan TLC radiopharmaceutical scanner and Waters Alliance HPLC system and dual-absorbance detectors. Other products receiving new or enhanced support include the Agilent Binary-SL pump, Canberra MCA UniSpec detector, Gilson autosampler, Gilson FC204 fraction collector, LabLogic's own SoFie stop-flow system, the Mini-Scan TLC scanner, Shimadzu HPLC system, Shimadzu autosamplers and Xcalibur MS software.
Chromatography software update
DataApex has released the update of its chromatography software. Clarity version 2.7 brings new control drivers covering Hitachi LaChrom Elite HPLC system (L-2100/2130 pump, L-2200 autosampler, L-2300 Column Oven, L-2400 UV Detector) and the HTA autosampler HT800L. According to the company, the software can now control more than 250 instruments. The new version enhances several functionalities that bring users more comfort during installation and configuration. The update is available for current users free-of-charge. The demonstration version and the complete list of controlled instruments can be downloaded from the company's website.
Online calculator for method conversion
Phenomenex has announced a new web-based tool to optimize customer HPLC methods for use with the company's Kinetex core-shell columns. The benefits to be gained by switching from fully-porous particle columns are also calculated. With the calculator, researchers input their method running conditions and details regarding current chromatographic results. According to the company, in less than one minute, the calculator delivers an optimized method with the recommended column and optimal run conditions for the user's system, whether it's HPLC or UHPLC. The calculator also provides expected backpressures, efficiency gains, solvent reduction, time savings and resolution improvements. The calculator can process details of both isocratic and gradient methods.
SPME GC-MS–Based Metabolomics to Determine Metabolite Profiles of Coffee
November 14th 2024Using a solid phase microextraction gas chromatography-mass spectrometry (SPME GC-MS)-based metabolomics approach, a recent study by the School of Life Sciences and Technology at Institut Teknologi Bandung (Indonesia) investigated the impact of environmental factors (including temperature, rainfall, and altitude) on volatile metabolite profiles of Robusta green coffee beans from West Java.
RP-HPLC Analysis of Polyphenols and Antioxidants in Dark Chocolate
November 13th 2024A recent study set out to assess the significance of geographical and varietal factors in the content of alkaloids, phenolic compounds, and the antioxidant capacity of chocolate samples. Filtered extracts were analyzed by reversed-phase high-performance liquid chromatography (RP-HPLC) with ultraviolet (UV) and spectrophotometric methods to determine individual phenolics and overall indexes of antioxidant and flavonoid content.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Katelynn Perrault Uptmor Receives the 2025 LCGC Emerging Leader in Chromatography Award
Published: November 13th 2024 | Updated: November 13th 2024November 13, 2024 – LCGC International magazine has named Katelynn A. Perrault Uptmor, Assistant Professor of Chemistry at the College of William & Mary, the recipient of the 2025 Emerging Leader in Chromatography Award. This accolade, which highlights exceptional achievements by early-career scientists, celebrates Perrault Uptmor’s pioneering work in chromatography, particularly in the fields of forensic science, odor analysis, and complex volatile organic compounds (VOCs) research.
