LCGC Magazine is pleased to announce the addition of David S. Bell to its editorial advisory board.
Over the past 20 years, Bell has worked directly in the chromatography industry, focusing his efforts on the design, development, and application of chromatographic stationary phases to advance liquid chromatography and related hyphenated techniques.
He is a research and development manager in the HPLC Surface Chemistry and Health Sciences Research department at Sigma-Aldrich/Supleco.
Bell’s main objectives have been to create and promote novel liquid chromatography (LC) technologies and to conduct research on molecular interactions that contribute to retention and selectivity in an array of chromatographic processes. His research results have been presented in numerous symposia worldwide, and have resulted in several peer-reviewed journal and trade magazine articles.
Bell’s undergraduate studies were done at the State University of New York at Plattsburgh (SUNY Plattsburgh). He received his PhD in analytical chemistry from The Pennsylvania State University (State College, Pennsylvania) and spent the first decade of his career in the pharmaceutical industry performing analytical method development and validation employing various forms of chromatography and electrophoresis.
Presenting GC Data Comparisons to Laypersons to Understand Potential Courtroom Implications
January 6th 2025In forensic science, scientific testimony is routinely presented in court to juries who may have limited or no scientific background, putting law enforcement and defense personnel in the position of having to make rapid decisions in short timeframes based on findings of which they are not specialists. Katelynn Perrault Uptmor, Assistant Professor of Chemistry at William & Mary (Williamsburg, Virginia) believes that the introduction of new technologies into the framework of routine forensic analysis must therefore bridge the gap between introduction of new and novel analytical science and the communication of that science to a court of law, and that analytical chemistry research must be mindful of the need to fill this gap in promoting new technologies.
Detailed Glycosylation Analysis of Therapeutic Enzymes Utilizing Comprehensive 2D-LC–MS
January 3rd 2025In this article, the use of comprehensive two-dimensional liquid chromatography (LC×LC) coupled to mass spectrometry (MS) for characterizing glycosylation of therapeutic enzymes is presented.
Advancing Gene Therapy: Enzyme Selection for Effective RNA Oligonucleotide Mapping
New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), continue to make progress in both primate and first-in-human trials. As this progress builds, the industry remains accountable for characterizing these molecules to meet the requirements of regulatory authorities.