Most readers of LCGC are no doubt familiar with the debate that has been going on within the field of analytical chemistry concerning the conference industry.
Most readers of LCGC are no doubt familiar with the debate that has been going on within the field of analytical chemistry concerning the conference industry. Are in-person events becoming less popular? Will budget-tightening impact attendance significantly in 2010? And so on. While there is certainly some validity to the theory that in-person meetings in general are not as business-critical as they once were, to get an idea of how the staff of LCGC feels about this debate, one has only to look at the schedule of events we have planned for Pittcon 2010, set to run from February 28 to March 5 in the Orange County Convention Center in Orlando, Florida.
Perhaps the biggest event planned is the LCGC/Spectroscopy Podcast Theater, set to run Monday, March 1 through Wednesday, March 3 at Booth 2805 in the convention center. A lineup of the industry’s most respected and well-known experts will be speaking throughout the first two days of the theater, bringing listeners cutting-edge information on HPLC/UHPLC, GC, GC–MS and LC–MS, and spectroscopic techniques in general. The third day will be dedicated to the launch of LCGC’s new online social networking and training site, CHROMacademy, and will also feature speakers from all corners of the chromatography field. We invite conference-goers to stop by the theater any time during these first three days of Pittcon. Morning sessions will run from 10–12 A.M., while afternoon sessions will run from 2–5 P.M., and free giveaways will be distributed to all who attend. When you add to this the Third Annual LCGC Awards press conference, to be held Monday at 2 P.M. in Room 303ABC, it is clear that LCGC’s slate will be full at this year’s Pittcon.
While the future of the conference industry may be the subject of debate for many, for LCGC, Pittcon 2010 promises to be the biggest and most elaborate in the 28-year history of the publication. For us, there really is no debate: Pittcon 2010 is still the biggest event in the field of separation science. We look forward to seeing you there.
Determining Neurotransmitters in Spinal Cords with UHPLC
February 18th 2025Researchers at Jilin University (Changchun, China) developed a highly sensitive, rapid, and accurate method for analyzing neurotransmitters (NTs) in rat spinal cord tissue. Ultra-high performance liquid chromatography-triple quadrupole tandem mass spectrometry (UHPLC-QqQ-MS/MS) in conjunction with ultra-ionic liquid dispersive liquid-liquid microextraction (UA-MIL-DLLME) were used to extract NTs for analysis.
The Next Frontier for Mass Spectrometry: Maximizing Ion Utilization
January 20th 2025In this podcast, Daniel DeBord, CTO of MOBILion Systems, describes a new high resolution mass spectrometry approach that promises to increase speed and sensitivity in omics applications. MOBILion recently introduced the PAMAF mode of operation, which stands for parallel accumulation with mobility aligned fragmentation. It substantially increases the fraction of ions used for mass spectrometry analysis by replacing the functionality of the quadrupole with high resolution ion mobility. Listen to learn more about this exciting new development.
Revolutionizing LC-MS with Next-Gen Separation for Cyclic Peptide Analysis
February 17th 2025Cyclic peptides, known for their stability and high specificity, are promising therapeutic agents in the fight against cancer, infections, and autoimmune diseases. However, developing effective cyclic peptides presents numerous challenges, including poor pharmacokinetics, efficacy, and toxicity. Traditional methods like liquid chromatography tandem-mass spectrometry (LC-MS/MS) often struggle with resolving isomeric linear peptide metabolites, posing significant risks in safety, efficacy, and regulatory approval. In this paper, Komal Kedia, PhD, will share how she leveraged MOBIE’s high-resolution ion mobility-mass spectrometry (IM-MS) system to achieve a 72% reduction in run times, 200% greater resolving power, and enhanced accuracy in identifying “soft spots” prone to enzymatic degradation.