Sample preparation is one of the most critical steps of the development and application of an analytical methodology.
Sample preparation is one of the most critical steps of the development and application of an analytical methodology. Especially when it comes to the analysis of challenging analytes in complicated matrices, efficient sample pretreatment ensures both preconcenration and selectivity enhancement.
On this basis, automation could further contribute to the efficiency of a sample pretreatment protocol offering increased precision and robustness, high sampling throughput and possibilities for process analytical (PAT) applications under demanding industrial environments.
Removing Double-Stranded RNA Impurities Using Chromatography
April 8th 2025Researchers from Agency for Science, Technology and Research in Singapore recently published a review article exploring how chromatography can be used to remove double-stranded RNA impurities during mRNA therapeutics production.
The Effect of Time and Tide On PFAS Concentrations in Estuaries
April 8th 2025Oliver Jones and Navneet Singh from RMIT University, Melbourne, Australia discuss a recent study they conducted to investigate the relationship between tidal cycles and PFAS concentrations in estuarine systems, and offer practical advice on the sample preparation and LC–MS/MS techniques they used to achieve the best results.