Sponsored Content - EU
Automated metabolic stability assays with sample incubation and LC-MS/MS determination are presented for use in drug metabolism and pharmacokinetic (DMPK) laboratories.
Therapeutic oligonucleotide analysis without ion-pair reagents (Nov 2024)
This non-IP-RP method, using ammonium bicarbonate as mobile phase additive, is highly sensitive and suitable for the bioanalysis of therapeutic oligonucleotides.
Comprehensive high-resolution analysis of signalling lipids
The optimized LC-MS/MS method covering 388 signaling lipids shows that the bioinert coated YMC Accura Triart C18 column combines high sensitivity with high resolution.
Native AEX-MS Analysis of IgG4-based mAbs (Oct 2024)
In this application note, the charge variant characterisation of IgG4-based mAbs was performed using a BioPro IEX QF anion exchange column coupled to an MS detector.
NTS of Polar Metabolites in Human Plasma (Oct 2024)
The non-targeted screening of polar metabolites in human plasma with high sensitivity is achieved using a bioinert YMC Accura Triart Diol HILIC column.
Fast Lipidomic Analysis with High Resolution (Oct 2024)
The analysis of human plasma samples using a bioinert coated YMC Accura Triart C8 column demonstrates that real-life lipidomic analysis in under 10 minutes is possible.
Therapeutic oligonucleotide analysis without ion-pair reagents