Analytical electronic laboratory notebook for discovery/QC
Waters
Waters® SDMS Vision Publisher™ is an extended capability of the NuGenesis® Scientific Data Management System which adapts to support existing free-flow or process driven workflows. SDMS Vision Publisher allows structured scientific documents to be easily created from predefined templates. Add selected content by interactively or automatically extracting information from NuGenesis SDMS, Empower™, MassLynx™ Software, or other applications. With SDMS Vision Publisher, you can create queries against single or multiple databases to locate data that otherwise could take hours or days to find looking through paper documentation. Vision Publisher automatically imports information - you can integrate captured information from the SDMS repository into Vision Publisher documents or integrate content managed by other software In addition to providing regulatory safeguards, SDMS Vision Publisher ensures the authenticity of electronic records and is certified to support the SAFE BioPharma digital identity and signature standard.
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The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO® OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
