Aligning Analytical Techniques with Modernized USP Monographs

A pilot study investigating whether nicotinamide adenine dinucleotide kinase (NADK) expression is selectively diminished in alcohol-associated liver cirrhosis (AC), as well as evaluating its potential as a biomarker for this condition, measured AC and non-AC (NAC). Nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+) levels in human liver samples were measured using liquid chromatography-mass spectrometry (LC-MS).

Bacteriophages are vital for addressing antibiotic-resistant bacteria, though phage therapies are currently rare. University of Lisbon researchers recently created a new purification workflow to address these concerns.

LCGC EAB member Paul Ferguson has been named a professor by special appointment at the Faculty of Science at the University of Amsterdam.

Aroma analysis is of paramount importance in the plant-based meat replacement industry. The ability to replicate flavors and mimic real meat is vital in appealing to consumers. To capture the full aroma profiles of cooked meat, analysts need dynamic purge techniques, such as dynamic headspace (DHS) sampling. The considerable water content in meat and other food brings risk of moisture build-up in the sorbent tube, potentially disrupting the TD-GC-MS analysis. An automated DHS option with dry purge feature, can effectively address this issue, as illustrated here using cooked ground beef and plant-based meat as examples. A workflow for optimizing DHS settings relevant to this study is presented. The aroma profiles of cooked ground beef and plant-based meat are analyzed and compared.