The 10th annual International Conference on Packed Column SFC (pcSFC) will be held 5–7 October 2016 at the Melia’ Vienna hotel in Vienna, Austria.
Photo Credit: Manchan/Getty Image
The 10th annual International Conference on Packed Column SFC (pcSFC) will be held 5–7 October 2016 at the Melia’ Vienna hotel in Vienna, Austria. The conference alternates annually between the United States and Europe and is the preeminent conference on supercritical fluid chromatography (SFC). Previous meetings were SFC 2015 Philadelphia, PA, USA; SFC 2014 Basel Switzerland; SFC 2013 Boston, MA, USA; SFC 2012 Brussels, Belgium; SFC 2011 New York City, USA; SFC 2010 Stockholm, Sweden; SFC 2009 Philadelphia, USA; SFC 2008 Zurich, Switzerland; SFC 2007 Pittsburgh, PA, USA. The symposium is dedicated to bringing scientists in industrial, academic, and government laboratories together to discuss the latest advances in packed column supercritical fluid chromatography. Each conference has been organized by the Green Chemistry Group. The complete SFC 2016 program and many of the oral and poster presentations from previous meetings and SFC 2016 can be found in their entirety at www.greenchemistrygroup.org/index.html.
SFC utilizes carbon dioxide as the main mobile phase component and can be a greener separation technology relative to high performance liquid chromatography (HPLC). pcSFC has become the method of choice for both preparative chiral and achiral separations up to 1 kg scale. In addition, analytical scale pcSFC provides a platform that affords faster separations than HPLC and can be readily interfaced with a variety of sample preparation methods. With appropriate stationary phases and mobile phase components, separation mechanisms can be normal phase, reversed phase, ion pair, and HILIC-like for example. Recent advances in analytical equipment have allowed SFC to move into validated environments, which have further expanded the use of pcSFC worldwide. With the continued growth of pcSFC as a cutting-edge technology, the conference provides a forum for new developments and applications. SFC 2016 promises to attract distinguished scientists from around the world to discuss advances in an environmentally-friendly technology.
The conference begins with a half-day short course on 5 October. Course instructors Larry Taylor (Virginia Tech), David Pinkston (Kellogg), and Larry Miller (Amgen) have a combined 50+ years of SFC experience. Topics that will be covered include: 1) History and Fundamentals of Analytical SFC, 2) Chiral and Achiral pcSFC Method Development, and 3) Preparative pcSFC. The course will be of interest to scientists with little SFC experience as well as those who are more experienced in the field.
Days two and three (6–7 October) include both oral and poster presentations. Speakers will include Caroline West and Eric Lesellier from Universite d’ Orleans, France; Lucie Novakova from Charles University Czech Republic; Eric Francotte from Norvatis, Zurich, Switzerland; Debby Mangelings from Vrije Universiteit, Belgium; and Ray McClain from Merck & Co., USA.
All topics related to pcSFC will be covered during the conference. Contributed abstracts have been submitted for both oral and poster presentations from laboratories in Sweden, Switzerland, Germany, Japan, Belgium, France, England, Czech Republic, and the U.S. Further details related to SFC 2016 can be found at http://greenchemistrygroup.org.
Program Co-Chair: Larry Taylor
E-mail: ltaylor@vt.edu
Website: http://greenchemistrygroup.org
The Complexity of Oligonucleotide Separations
January 9th 2025Peter Pellegrinelli, Applications Specialist at Advanced Materials Technology (AMT) explains the complexity of oligonucleotide separations due to the unique chemical properties of these molecules. Issues such as varying length, sequence complexity, and hydrophilic-hydrophobic characteristics make efficient separations difficult. Separation scientists are addressing these challenges by modifying mobile phase compositions, using varying ion-pairing reagents, and exploring alternative separation modes like HILIC and ion-exchange chromatography. Due to these complexities, AMT has introduced the HALO OLIGO column, which offers high-resolution, fast separations through its innovative Fused-Core® technology and high pH stability. Alongside explaining the new column, Peter looks to the future of these separations and what is next to come.
Metabolomics Analysis of Low Birth-Weight Infants Using UHPLC-MS/MS Following Lipid Emulsion
January 10th 2025A recent study aimed to directly compare the changes in serum metabolites among very low birth-rate (VLBW) infants following the administration of the soybean oil-based lipid emulsion and soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) lipid emulsion using untargeted metabolomics techniques.
Analyzing New Drug Modalities: An ISC 2024 Interview with Kelly Zhang
January 10th 2025At ISC 2024 in Liverpool, United Kingdom, LCGC International interviewed Kelly Zhang of Genentech about her work analyzing new drug modalities, such as mRNA, oligonucleotides, peptides, and cell and gene therapies.