Trends

This article provides an introduction to electrochemical liquid chromatography mass spectrometry. The instrumental set-up is presented and selected applications in drug development processes are discussed.

In this installment of "Column Watch," Ron Majors looks at the results of a recent HPLC column survey conducted by LCGC North America.

In this installment of "Column Watch," Ron Majors looks at the results of a recent HPLC column survey conducted by LCGC North America.

Complete 2009-2010 Buyers' Guide listings via Nxtbook.

This month's Technology Forum looks at the topic of HPLC/Ion Chromatography Focus and the trends and issues surrounding it. Joining us for this discussion is Chris Pohl, VP and Chief Science Officer at Dionex Corporation, Larry Tucker from Metrohm-Peak, and Yuichi Fusho of Shodex.

Enabling targeted quantitative proteomics applications and hypothesis-driven inquiries will help researchers to understand how proteins function in living systems. The discovery and validation of small molecule and protein-based biomarkers, and the eventual translation of these discoveries from the research lab to the clinic, involves robust mass spectrometry (MS) systems and software that make it easier for technicians to perform routine sample analyses on liquid chromatography (LC)–MS-MS systems, which continue to be used in an increasing number of both protein and small molecule analysis applications.

Majors analyzes results from LCGC's GC user survey, which was conducted in January 2003.

Ron Majors analyzes results from LCGC's recent sample prep user survey.

This installment of "Milestones in Chromatography" looks at two major international meetings held in Las Vegas, Nevada, and Seattle, Washington, that were pivotal in the early development of HPLC.

In this month's "Column Watch," Majors recounts some of the more interesting paper and poster presentations given at HPLC '99, held May 30–June 4, in Grenada, Spain.