Why Do Peaks Tail?
John Dolan discusses the causes of peak tailing, how to measure it, preventive measures, and why newer column types are less prone to tailing problems.
Validation of Impurity Methods, Part I
This column is the first installment in a two-part series reviewing ICH and FDA impurity method validation guidelines.
Analysis of Various Cyanobacterial Toxins by LC–MS
This article focuses on the initial development of an LC–MS method to screen for cyanotoxins at low parts-per-billion levels.
ASTM Subcommittee E13.19 on Chromatography
John Hinshaw writes about the role that the American Society for Testing and Materials International plays in chromatography standardization.
The Use of Micrometer-Sized Particles in Ultrahigh Pressure Liquid Chromatography
The guest authors describe capillary columns for ultrahigh pressure liquid chromatography.
