September 2022

This article presents a new hydrophilic SAX hybrid monolithic column prepared by in‑capillary coating 5 μm bare silica particles with functional organic polymers. After preparation conditions were investigated and selected, the resulting column was characterized in detail.

A critical step in any troubleshooting exercise—but one that I think is underappreciated—is recognizing that there is a problem to be solved.

Key insights on how to get the most out of gas chromatography for the most difficult problem solving, the best quantitative analysis, and the highest data integrity.

This instalment of “Column Watch” presents many of the highlighted topics and trends observed at the symposium.

As I write this, I’m also grading the final exam from my Chromatography and Separations course. Here’s your opportunity to test yourself; answers are provided.

This article explores potential pitfalls associated with 1D‑LC and how 2D‑LC can overcome these obstacles.