Torrey Mesa Research Institute, 3115 Merryfield Row, San Diego, California 92121.
Analysis of Combinatorial Natural Products by HPLC and CE
February 1st 2004In this article the authors report on a combinatorial natural product discovery methodology that uses a viral vector system to transfer secondary metabolite-related enzymes from C. roseus to tobacco cell cultures. Using high-resolution separation techniques, including HPLC, CE and MS, they describe the analysis of secondary metabolite patterns.